Association between morphometric variables and nocturnal desaturation in sickle-cell anemia

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Association between morphometric variables and nocturnal desaturation in sickle-cell anemia.

OBJECTIVE to evaluate associations between morphometric variables, cervical circumference (CC), and abdominal circumference (AC) with the presence of nocturnal desaturation in children and adolescents with sickle-cell anemia. METHODS all patients were submitted to baseline polysomnography, oral cavity measurements (maxillary intermolar distance, mandibular intermolar distance, and overjet), a...

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Nocturnal Enuresis in Children and Adolescent with Sickle cell Anemia

Children with sickle cell anemia (SCA) have a tendency to have nocturnal enuresis (NE) more than normal children with males being more affected than females. Mechanisms of NE that operate in normal children probably do so in children with SCA. Postulated causes of nocturnal enuresis in individuals with SCA include hyposthenuria causing nocturnal polyuria, reduced bladder capacity or nocturnal b...

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Nocturnal oxyhemoglobin desaturation and arteriopathy in a pediatric sickle cell disease cohort

OBJECTIVE The purpose of this study of sickle cell disease (SCD) was to determine whether arteriopathy, measurable as intracranial vessel signal loss on magnetic resonance angiography (MRA), was associated with low nocturnal hemoglobin oxygen saturation (SpO2) or hemolytic rate, measurable as reticulocytosis or unconjugated hyperbilirubinemia. METHODS Ninety-five East London children with SCD...

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Background: Hemoglobin S arises is the result of a point mutation (A-T) in the sixth codon on the -globin gene on chromosome 11 causing sickle cell anemia. The presence of fetal hemoglobin in infancy plays a relatively protective role for vaso-occlusive symptoms that are the major contributor for the morbidity and mortality among patients with sickle cell anemia. hydroxyurea, an s-phase-specif...

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ژورنال

عنوان ژورنال: Jornal de Pediatria

سال: 2014

ISSN: 0021-7557

DOI: 10.1016/j.jped.2014.01.005